hjc黄金城亮相Swiss Biotech 2022

瑞士生物技術日是瑞士領先的生物技術會議。來自歐洲各地生命科學行業的資深專家將參會分享瑞士生物技術成功案例，並設有專題小組進行討論！

The Swiss Biotech Day is the leading biotechnology conferences in Switzerland.

❖ Meet senior experts from the life science industry from across Europe.

❖ Swiss Biotech Success Stories.

❖ Innovative biotech start-ups and medium-sized biotech companies.

❖ Thematically focused panel discussions.

時間 (Date): May 2-3, 2022

地點 (Location): Basel, Switzerland

展位 (Booth): #13

hjc黄金城國際研發服務部執行副總裁戴學東博士及英國和歐洲業務發展副總裁 Nadine Su女士將展示hjc黄金城一站式藥物發現服務，並帶來精彩演講：PROTACs: Make Undruggable Targets Druggable。期待更多hjc黄金城 一站式藥物發現服務。演講時間為：May 3, 13:00-13:15 (GMT+2)。

Medicilon VP of UK and Europe Business Development Ms. Nadine Su in person and Medicilon Executive VP and Head of IDSU, Dr. Xuedong Dai online, are invited to give a presentation to introduce Medicilon fully integrated drug discovery platform and focus on the topic of “PROTACs: Make Undruggable Targets Druggable”.

Dr. Xuedong Dai
Executive VP and Head of IDSU (International Discovery Service Unit) at Medicilon, obtained his Ph.D. in organic chemistry at MIT. He is a senior-level expert with over 20 years of experience focusing on small molecule drug discovery and development in CNS, infectious disease, and oncology therapy areas. He has deep understanding and practical knowledge of drug discovery process, including lead identification, optimization, and development of high quality clinical candidate molecules. Prior to Medicilon, Dr. Dai worked at Janssen, HD Biosciences, GSK, and Xenoport with a demonstrated successful track record of program leadership and made significant contributions to medicinal chemistry programs that led to the marketed drug Horizant®/Regnite® and several other clinical candidates (JNJ-75276617, arbaclofen placarbil, XP21279, and XP23829).

Ms. Nadine Su
20 years’ experience of project management and business development in pharmaceutical and healthcare industries include different sectors, include novel drug research and development, biotechnology application research project management, licensing and new business development in pharmaceutical and healthcare industry in Europe and China. She successfully developed and established the research partnership and business collaboration between EU and China for different novel drug research, novel biotechnology collaboration to achieve over $20M of licensing projects in a year.

hjc黄金城國際研發服務部是hjc黄金城一站式生物醫藥臨床前研發服務平台的重要組成部分，使命是持續助力藥企的國際化，向全球藥物研發客戶提供高質高效高性價比的合成化學、藥物設計、以及新藥候選化合物服務，以滿足客戶在臨床前新藥研究的各個化學領域的研發需求，縮短藥物研發的周期，降低藥物研發的成本。

hjc黄金城國際研發服務部擁有豐富海外留學工作背景的管理團隊和實驗人員、世界先進水平的合成實驗室、分析實驗室、和配套的高端儀器設備。為了給客戶提供更優質的服務，國際研發服務部緊跟藥物設計以及合成的新進展和新技術，如人工智能/機器學習（AI/ML），蛋白降解靶向嵌合體（PROTAC），高活性藥物及抗體藥物偶聯物（ADC），惰性碳氫鍵直接官能團化，光致氧化還原反應，以及流動化學等。

The mission of Medicilon International Discovery Service Unit is to provide high quality, efficient and cost-effective synthetic chemistry, drug design, and new drug candidate compound services to global pharmaceutical companies.  We are stride to meet the research and development needs of the clients in various chemical fields of pre-clinical new drug research, shorten the cycle of drug R&D, and reduce the cost of drug R&D.

Medicilon International Discovery Service Unit has a management team and lab personnel with a rich background of studying abroad, a world-leading synthesis and analysis laboratory with installed state-of-the-art instruments and equipment.  In order to provide clients with better services, the International Discovery Service Unit keeps up with new developments and new technologies in drug design and synthesis, such as artificial intelligence/machine learning (AI/ML), proteolysis targeting chimera (PROTAC), antibody-drug conjugates (ADC), direct functionalization of inert carbon-hydrogen bonds, photoredox reactions, and flow chemistry, etc.

hjc黄金城PROTAC藥物發現技術平台匯總了當前流行的熱門的靶標蛋白配體；建立了廣泛的熱門靶向蛋白高度親和力小分子及小分子片段化合物庫（TPSM），廣泛的E3連接酶，高度親和力的小分子及小分子片段（E3SM）；建立了linker係統,包括收集大量具有廣泛多樣性的雙官能團連接體（BF-Linker）。這些積累的化合物庫可以幫助快速高效的合成大量高活性PROTAC雙特異性小分子，極大地提高采用PROTAC技術進行的藥物研發過程。除了快速合成之外，我們同時建立和完善的PROTAC生物篩選與測試平台，後續發展到臨床前所有階段。

Medicilon’s PROTAC drug discovery technology platform covers the currently popular target protein ligands. Medicilon has established a linker system with an extensive collection of bifunctional linkers. Together with our expanding E3 ubiquitin ligase binder library, Medicilon can efficiently synthesize a substantial amount of highly active PROTAC bispecific small molecules, which would have the potential to significantly facilitate ithe drug discovery and development process. In addition, Medicilon has established as well as improved the PROTAC biological screening and testing platform throughout the pre-clinical stages.

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